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These articles represent the success stories of researchers using CapNMR™ probes in their scientific applications. Our goal is to provide a one-stop library resource for these articles. It's a long and ever-growing list, please check back often! Technical Advances: Method, Workflow and Productivity Evolving Trends in the Dereplication of Natural Product Extracts: New Methodology for Rapid, Small-Scale Investigation of Natural Product Extracts Gerhard Lang, Nor Ainy Mayhudin, Maya I. Mitova, Lin Sun, Sonia van der Sar, John W. Blunt, Anthony L. J. Cole, Gill Ellis, Hartmut Laatsch, and Murray H. G. Munro J. Nat. Prod. 2008 ,71(9), 1595-1599. High-Throughput Natural Product Chemistry Methods and the Application of the Capillary NMR Probe Jinfeng Hu, Gary R. Eldridge, Yihua Yu, Mark O’Neil-Johnson Progress in Chemistry (China) 2008, 20(4), 429-440. Optimized liquid chromatography-mass spectrometry approach for the isolation of minor stress biomarkers in plant extracts and their identification by capillary nuclear magnetic resonance Gaetan Glauser, Davy Guillarme, Elia Grata, Julien Boccard, Aly Thiocone, Pierre-Alain Carrupt, Jean-Luc Veuthey, Serge Rudaz, Jean-Luc Wolfender Journal of Chromatography A:2008, 1180, 90-98. (NMR part is discussed in the paper) UPLC-TOF-MS for Plant Metabolomics: A Powerful Tool for Discriminating Stress States in Plants and Detecting Low-Level Wound Biomarkers Glauser G., Grata E., Boccard J., Marsden-Edwards E., Major H., Carrupt P.-A., Rudaz S., and Wolfender J.-L. American Laboratory, On-line Edition:Jun 2008, Posted On: 6/27/2008. (Focused on LC-MS) Development of Ultrahigh-Throughput NMR Spectroscopic Analysis Utilizing Capillary Flow NMR Technology Nigel J. C. Bailey and Ian R. Marshall Analytical Chemistry 2005, 77, 3947-3953. Synthesis Chemistry Determination of regulatory phosphorylation sites in nanogram amounts of a synthetic fragment of ZAP-70 using microprobe NMR and on-line coupled capillary HPLC-NMR Petra Hentschel, Manfred Krucker, Marc David Grynbaum, Karsten Putzbach, Rainer Bischoff, Klaus Albert Magn. Reson. Chem. (2005), 43, 747-754 Macrocyclic Disulfides for Studies of Sensitized Photolysis of the S-S Bond Z. Huang, Q-Z Yang, T. Kucharski, D. Khvostichenko, S. Wakeman, and R. Boulatov Chem. Eur. J. (2009), 15, 5212-5214
Metabolomics/Metabonomics
Optimized liquid chromatography-mass spectrometry approach for the isolation of minor stress biomarkers in plant extracts and their identification by capillary nuclear magnetic resonance
Gaetan Glauser, Davy Guillarme, Elia Grata, Julien Boccard, Aly Thiocone, Pierre-Alain Carrupt, Jean-Luc Veuthey, Serge Rudaz, Jean-Luc Wolfender
Journal of Chromatography A:2008, 1180, 90-98. (NMR part is discussed in the paper)
Differential Analysis of Mycoalexins in Confrontation Zones of Grapevine Fungal Pathogens by Ultrahigh Pressure Liquid Chromatography/Time-of-Flight Mass Spectrometry and Capillary Nuclear Magnetic Resonance Glauser G., Gindro K., Fringeli J., de Joffrey J.-P., Rudaz S., and Wolfender J.-L. Journal of Agricultural and Food Chemistry 2009, 57, 1127-1134 Detection of epithelial ovarian cancer using 1H-NMR-based metabonomics Kunle Odunsi, Robert M. Wollman, Christine B. Ambrosone, Alan Hutson, Susan E. McCann, Jonathan Tammela, John P. Geisler, Gregory Miller, Thomas Sellers, William Cliby, Feng Qian, Bernadette Keitz, Marilyn Intengan, Shashikant Lele and James L. Alderfer Int. J. Cancer:2005, 113, 782-788. Medicinal Chemistry Natural Products Evolving Trends in the Dereplication of Natural Product Extracts: New Methodology for Rapid, Small-Scale Investigation of Natural Product Extracts Gerhard Lang, Nor Ainy Mayhudin, Maya I. Mitova, Lin Sun, Sonia van der Sar, John W. Blunt, Anthony L. J. Cole, Gill Ellis, Hartmut Laatsch, and Murray H. G. Munro J. Nat. Prod. 2008 , 71(9), 1595-1599. Laxanol, a new 2,5-diaryl-3,4-dihydroxymethyltetrahydrofuran type lignan from Justicia laxa. Hu, J.F., Starks, C., Garo, E., Hough, G., Rice, S., Goering, M.G., O'Neil-Johnson, M., Eldridge, G.R. Journal of Chemical Research, 2008, 1, 20-21. Acuminatanol, the first 2',2'''-bis-dihydrobiflavonol from the Aqueous Extract of Trichoscypha acuminata Hu, J.F.; Garo, E.; Hough, G.; Goering, M.; O’Neil-Johnson, M.; Eldridge, G.R. Tetrahedron Letters, 2007, 48, 5747-5749 Isoflavones from Psorothamnus arborescens via High-throughput Natural Product Chemistry Methods Hu, J.F.; Garo, E.; Hough, G.; Goering, M.; Yoo, H.D; O’Neil-Johnson, M.; Eldridge, G.R. Journal of Chemical Research, 2007, 5, 296-297 Anti-HCV Bioactivity of Pseudoguaianolides from Parthenium hispitum. Jin-Feng Hu, R. Patel, B. Li, Elaine Garo, Grayson Hough, Matt Goering, Hye-Dong Yoo, Mark O'Neil-Johnson, and Gary Eldridge Journal of Natural Products, 2007, 70, 604-607. Bacterial Biofilm Inhibitors from Diospyros dendo Jin-Feng Hu, Eliane Garo, Matt G. Goering, Mark Pasmore, Hye-Dong Yoo, Tim Esser, Jennifer Sestrich, Peadar A. Cremin, Grayson W. Hough, Peter Perrone, Yin-Shi L. Lee, Ngoc-Tram Le, Mark O'Neil-Johnson, John W. Costerton, and Gary R. Eldridge Journal of Natural Products 2006, 69, 118-120. Phytochemistry in the microgram domain - a LC-NMR perspective Jean-Luc Wolfender, Emerson F. Queiroz, Kurt Hostettmann Magn. Reson. Chem. 2005; 43: 697-709. Suaveolindole, a New Mass-Limited Antibacterial Indolosesquiterpene from Greenwayodendron suaveolens Obtained via High-Throughput Natural Products Chemistry Methods Hye-Dong Yoo, Peadar A. Cremin, Lu Zeng, Eliane Garo, Caroline T. Williams, Chris M. Lee, Matt G. Goering, Mark O'Neil-Johnson, Gary R. Eldridge, and Jin-Feng Hu Journal of Natural Products 2005; 68 (1), 122-124, Miniaturization of the Structure Elucidation of Novel Natural Products - Two Trace Antibacterial Acylated Caprylic Alcohol Glycosides from Arctostaphylos pumila Jin-Feng Hu, Hye-Dong Yoo, Caroline T. Williams, Eliane Garo, Peadar A. Cremin, Lu Zeng, Hélène C. Vervoort, Chris M. Lee, Shane M. Hart, Matt G. Goering, Mark O'Neil-Johnson, and Gary R. Eldridge Planta Med. 2005, 71, 176-180.F High Throughput Method for Natural Products Library Gary R. Eldridge, Hélène C. Vervoort, Chris M. Lee, Peadar A. Cremin, Caroline T. Williams, Shane M. Hart, Matt G. Goering, Mark O'Neil-Johnson, and Lu Zeng Analytical Chemistry 2002, 74, 3963-3971.
Separations
Food Science Proteomics Microflow NMR Technology Reviews
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